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楊靜
宣布人:楊飛??宣布時候:2022-03-19?? 閱讀次數:436

楊靜,女,博士,特聘副研討員,碩士研討生導師。2017年畢業于姑蘇大學藥學院,取得醫學博士學位。2014-2017為姑蘇大學-哈佛大學麻省總病院結合培育博士,2017-2019哈佛大學麻省總病院博士后。2020年10月插手中國藥科大學工學院生物醫學工程教研室。今朝掌管有中國藥科大學高條理人材引進名目1項(100萬)。最近幾年來在Nature Communications, Chemical Science, Chemical Communications等國際權勢巨子期刊頒發論文20余篇。

 

接洽體例:yangjing@forestrivertimberhomes.com

 

研討標的目的:

1. 小份子光學探針的構建及在AD診療中的利用

2. 抗腫瘤卵白降解藥物份子的設想及活性研討

3. 棕色脂肪的成像研討

 

代表性論文:

 

1. Jing Yang#, Wei Yin#, Richard Van, Keyi Yin, Peng Wang, Chao Zheng, Biyue Zhu, Kathleen Ran, Can Zhang, Mohanraja Kumar, Yishan Shao, Chongzhao Ran. Turn-on chemiluminescence probes and dual-amplification of signal for detection of amyloid beta species in vivo. Nature Communications, 2020, 11(1), 1-14.

 

2. Jing Yang#, Biyue Zhu#, Wei Yin, Zhihao Han, Chao Zheng, Peng Wang, Chongzhao Ran. Differentiating Ab40 and Ab42 in amyloid plaques with a small molecule fluorescence probe. Chemical Science, 2020, 11 (20), 5238-5245.

 

3. Jing Yang#, Jian Yang#, Huan Wang, Junfeng Wang, Jianping Xiong, Chunhua Qiao, Chongzhao Ran.. Atom-economical design of PET tracer for imaging αvβ3 integrin via utilizing three-in-one function of 64Copper. Chemical Communications, 2020, 56 (12), 1788-1791.  

 

4. Jian Yang#, Jing Yang#, Yuyan Li, Yungen Xu,  Ran, C. Z. Near-infrared Fluorescence Ocular Imaging (NIRFOI) of Alzheimer’s Disease. Molecular Imaging and Biology, 2019, 21 (1), 35-43. 

 

5. Liguo Wang, Jing Yang*, Huan Wang, Chongzhao Ran, Ying Su, Long Zhao*. A highly selective turn-on fluorescent probe for the detection of aluminum and its application to bio-imaging. Sensors2019, 19 (11), 1-10.

 

6. Jing Yang, Jian Yang, Chongzhao Ran. Spectral Unmixing Imaging for Differentiating Brown Adipose Tissue Mass and Its Activation. Contrast Media & Molecular Imaging, 2018, 2018, 1-7.

 

7. Jing Yang#, Xueli Zhang#, Yiying Zhu, Emily Lenczowski, Yanli Tian, Jian Yang, Can Zhang, Markus Hardt, Chunhua Qiao, Rudolph E. Tanzi, Anna Moore, Hui Ye, Chongzhao Ran. A double-edged role of copper in the fate of amyloid beta in the presence of anti-oxidants. Chemical Science, 2017, 8 (9), 6155-6164.

 

 

8. Jing Yang, Zhengtao Tu, Xin Xu, Jinfeng Luo, Xing Yan, Chongzhao Ran, Xinliang Mao, Ke Ding, Chunhua Qiao. Novel Conjugates of Endoperoxide and 4-Anilinoquinazoline as Potent Anticancer AgentsBioorganic & Medicinal Chemistry Letters, 2017, 27 (6), 1341-1345.

 

9. Jing Yang#, Jian Yang#, Lu Wang, Anna Moore, Steven. H Liang, Chongzhao Ran. Yang, J., Yang, J., Wang, L., Moore, A., Liang, S. H., Ran, C. Z. Synthesis-free PET imaging of brown adipose tissue and TSPO via combination of disulfiram and 64CuCl2. Scientific Reports, 2017, 7, 1-9.

 

10. Jing Yang, Yanli Liu, Chengwen Xue, Wei Yu, Jian Zhang, Chunhua Qiao. Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. European Journal of Medicinal Chemistry, 2014, 86, 235-241.

 

11. Huanqiu Li#, Jing Yang#, Shuhua Ma, Chunhua, Qiao. Structure-based design of rhodanine-based acylsulfonamide derivatives as antagonists of the anti-apoptotic Bcl-2 protein. Bioorganic & Medicinal Chemistry, 2012, 20 (14), 4194-4200.

             注:# Equal contribution

 


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